How do I know if this product is working?

If you are taking Vitamin K2 supplements, there are a couple of ways of measuring its effect on your body. First is to measure bone density. You will need to work with your doctor to do this. Get a base reading and then measure 12 months later. Bone density is slow to budge, but it an be done with all bone- supporting nutrients (Vitamin D3 K2, Calcium, Magnesium, Vit C etc.) and exercise. Keep in mind that bone mineral density is influenced by several factors, not just K2, so this is an indirect test of efficacy. (Many customers note changes in dental plaque, but there is no published evidence, just anecdotal evidence.) Second, we know that Vitamin K2 deficiency causes lower levels of active osteocalcin, a protein found in bone and teeth. It is produced by bone-building cells, called osteoblasts. Low levels of active osteocalcin (or high levels of inactive osteocalcin) makes bones more fragile. Taking Vitamin K2 reduces the level of inactive osteocalcin, which suggests that it will making bones stronger. Talk to your doctor about getting osteocalcin or undercarboxylated Osteocalcin (ucOC) tests from labs like Genova, Quest, and LabCorp. There is another test being developed (hard to find and get done at this time) that measures undercarboxylated Osteocalcin (ucOC) for the effect of Vitamin K2 (MK4 and MK7) on artery walls and blood vessels. It is early days for this test. We hope that one day, these tests are as easy to get as a cholesterol reading, but we are not there yet.